berberine相关论文
目的:探讨小檗碱对小鼠代谢相关脂肪性肝病（MAFLD）致肝细胞程序性坏死的影响及其相关分子机制。方法:20只雄性C57BL/6N小鼠随机分为4......
目的:评价小檗碱对小鼠非酒精性脂肪性肝病程序性坏死的影响及其与腺苷酸活化蛋白激酶(AMPK)/转录活化因子6(STAT6)通路的关系。方......
Rapid and simultaneous determination of moisture and berberine content in Coptidis Rhizoma and Phell
Coptidis Rhizoma (Chinese: Huanglian) and Phellodendri Chinensis Cortex (Chinese: Huangbo) are widely used Traditional C......
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目的观察高糖环境下黄连素（BBR）对人视网膜血管内皮细胞（hREC）凋亡的抑制作用。方法将hREC分为空白对照组（NC组）、高糖组（HG组）、BBR处理组......
目的评价沉默信息调节因子1(SIRT1)/核因子E2相关因子2(Nrf2)信号通路在小檗碱减轻小鼠肾缺血再灌注损伤中的作用。方法SPF级健康......
小檗碱是一种异喹啉生物碱,具有多种药理作用。研究表明小檗碱可以通过影响多种途径发挥神经保护作用,包括PI3K/Akt/Bcl-2、Akt/Nr......
测定了15个原小檗碱衍生物(3-17)及小檗碱(1)和药根碱(2)抑制急性淋巴白血病细胞(包括Reh和Nalm-6细胞)增殖的活性。其中化合物4(9......
目的观察小檗碱(Berberine，BBR)联合炔雌醇醋酸环丙孕酮治疗肥胖型多囊卵巢综合征(Polycystic ovary syndrome，PCOS)的疗效及其对血......
目的通过比较黄连煎煮液和葛根芩连汤中小檗碱的煎出率大小，阐明中药复方的科学性。方法采用高效液相色谱法(HPLC)分别测定黄连单方......
目的探讨奥扎格雷钠联合盐酸小檗碱治疗急性脑梗死疗效及其对糖脂代谢的影响。方法将158例脑梗死急性期患者按数字表法随机分为使......
目的 探讨黄连索抑制鼠疫耶尔森菌(简称鼠疫菌)作用的分子机制.方法 应用鼠疫菌全基因组芯片表达谱进行黄连素作用鼠疫菌研究.液体......
目的 探讨黄连素对大鼠局灶性脑缺血再灌注后脑组织CDK4和cyclin D1表达的调节以及黄连素可能的脑保护作用机制.方法 50只雄性Wist......
Objective: To investigate the effect of berberine, one of the main alkaloids of Rhizoma coptidis, on myocardial orpholog......
用正交试验对十大功劳提取盐酸小檗碱的工艺进行研究。结果表明:A_2B_8C_1D_2E_3F_2即提取溶剂用0.5%硫酸,盐析用24%食盐,浸提温度......
Coptis Chinensis is a traditional Chinese medicine herb that has the effect of clearing heat and drying dampness,purging......
Coptis Chinensis is a traditional Chinese medicine herb that has the effect of clearing heat and drying dampness,purging......
小檗碱在临床上广泛运用于抗痢治疗,其抗菌作用被认为是其发挥抗痢作用的主要药理学机制。小檗碱的体内外抗菌活性明显,其抗菌机制......
Sankezhen(Berberidis Radix) is a traditional Chinese materia medica,cold in nature and bitter in taste,for treating synd......
Sankezhen(Berberidis Radix) is a traditional Chinese materia medica,cold in nature and bitter in taste,for treating synd......
本研究系统评价了20个9-取代小檗碱类似物的糖消耗活性,结果表明,在9位引入乙氧基有利于体外糖消耗活性的增加。9-乙氧小檗碱化合......
目的探讨金芪降糖片中黄连、黄芪和金银花配伍对主要活性成分小檗碱体内药动学的影响。方法雄性SD大鼠分别单次ig金芪降糖片(0.42 ......
Study on the inclusion interactions of berberine hydrochloride and cucurbit[7] by spectrofluorimetry
The inclusion interaction between berberine hydrochloride(BRH) and cucurbit[7](CB[7]) has been studied by spectro-fluori......
目的通过大鼠原代肝细胞模型,明确小檗碱、巴马汀和药根碱的肝细胞摄取特征。方法 Seglen两步法分离大鼠原代肝细胞并悬浮培养,应......
目的:观察盐酸小檗碱联合磷酸铝凝胶灌肠治疗小儿急性肠炎的临床疗效。方法:将150例急性肠炎患儿随机分为观察组和对照组各75例,两......
目的:探讨黄连素对人慢性髓系白血病细胞K562的作用及其机制。方法:将对数生长期的K562细胞随机分成对照组和黄连素组。对照组细胞......
Meta analysis of clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty l
Objective: To evaluate the clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver. Meth......
Objective:Berberine,a cationic alkaloid first isolated in 1917,has been approved by the China Drug Administration for de......
Efficacy and safety of berberine in the prophylactic treatment of acute radiation proctitis in posto
Objective The aiom of this study was to study the efficacy and safety of berberine as a prophylactic treatment of acute ......
OBJECTIVE:To evaluate the efficacy of Huanglian root decoction(黄连煎剂,HLD)on kidney injury in rat’s model of metaboli......
目的:比较表小檗碱和小檗碱与牛血清白蛋白（BSA）相互作用,并探讨与结构的关系。方法:采用荧光猝灭法与紫外分光光度法探讨表小檗碱和......
Berberine,an isoquinoline alkaloid isolated from the Chinese herb Coptis chinensis and other Berberis plants,has a wide ......
小檗碱在临床上主要用于治疗肠道感染,是我国传统药物.近年来研究发现小檗碱可通过抑制Th1、Th17细胞分化,调节Th1/Th2平衡,抑制T......
Combination of Evodiamine with Berberine Reveals a Regulatory Effect on the Phenotypic Transition of
Objective Transdifferentiation exists between stromal cells or between stromal cells and cancer cells. Evodiamine and be......
ROS?Responsive Berberine Polymeric MicellesEffectively Suppressed the Inflammationof Rheumatoid Arth
Rheumatoid arthritis (RA) is an autoimmune disease, which attacks human joint system and causes lifelong inflammatory co......
目的:探讨小檗碱联合他汀对稳定型冠心病患者血浆氧化三甲胺(TMAO)水平的影响。方法:将血管内超声检查证实的稳定型冠心病(单支血......
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
Beneficial effect of berberine on atherosclerosis based on attenuating vascular inflammation and cal
OBJECTIVE To investigate the beneficial effect of berberine(BBR)on atherosclerosisin Apo~(-/-) E mice and explore the un......
Berberine ameliorates chronic unpredictable mild stress induced depressive like behaviors and elevat
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
目的:研究小檗碱对去卵巢大鼠骨量丢失的作用。方法:以去卵巢诱导大鼠骨质疏松症,3月龄雌性SD大鼠随机分为假手术组、去卵巢组(空......
目的 探讨小檗碱对大鼠骨髓间质干细胞成脂分化的影响及其机制.方法 经分离纯化的大鼠骨髓间质干细胞,分为正常对照组,成脂分化诱......
目的 黄连素(BBR)对糖尿病及血脂异常的作用仍未完全阐明.该研究旨在研究BBR对高脂饮食诱导的肥胖(DIO)大鼠模型的作用机制.探索其......
目的研究黄连素对脂多糖(lipopolysaccharide，LPS)诱导的小鼠抑郁样行为及脑内白介素-1β(IL-1β)、肿瘤坏死因子-α (TNF-α)含量......
目的探讨黄连素(Ber)对实验性自身免疫性脑脊髓炎(EAE)大鼠脊髓内基质金属蛋白酶-9(MMP-9)、细胞间黏附分子-1(ICAM-1)的影响。方......
目的 观察小檗碱对脂多糖所致急性肺损伤大鼠血管内皮细胞生长因子(VEGF)及其受体-2(VEGFR-2)表达的影响,探讨小檗碱对急性肺损伤......
Effect of Berberine on Expression of Hepatocyte Nuclear Factor-4α in Rats with Fructose-induced Insu
The effects of berberine on the expression of hepatocyte nuclear factor-4α (HNF-4α) in liver of rats with fructose-ind......
Differences Between the Concentrations in Rabbit Body Fluid of Berberine Hydrochloride,Chlorogenic A
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
Anti-diabetic effects of cinnamaldehyde and berberine and their impacts on retinol-binding protein 4
Background Retinol binding protein 4 (RBP4),as an adipocyte secreted cytokine,was recently found to be inversely correla......
Berberine ameliorates renal injury in streptozotocin-induced diabetic rats by suppression of both ox
Background Berberine is one of the main constituents of Coptidis rhizoma (CR) and Cortex phellodendri, In this study, we......
